Dom Jefferies came into City’s starting line-up at Shrewsbury Town.
Jefferies is expected to feature at right-back, with Tendayi Darikwa moving into a central position.
The change is part of the strategy to manage Lewis Montsma’s games as he returns following his ACL injury.
Head coach Michael Skubala said: “It's my job to manage these situations for the club and for us as a team, but then it gives people an opportunity to come into the side and show what they can do to then keep the shirt.”
Imps: Wickens, Jefferies, Darikwa, O'Connor, Roughan, Erhahon, McGrandles, Hackett, House, Makama, Cadamarteri. Subs: Pardington, Bayliss, Hamilton, Duffy, Moylan, Street, Draper.
Shrews: Blackman, Hoole, Benning, M.Feeney, J.Feeney, Lloyd, Perry, Pierre, Bloxham, Castledine, Shipley. Subs: Savin, Rossiter, Kayode, Ojo, Gilliead, Marquis, O'Reilly